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Search Results for " experimental colitis "

9

Compounds

Cat No. Product Name Synonyms Targets
T12079 ML604440 Proteasome
ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.
T71691 Pumafentrine BY 343 PDE
Pumafentrine(BY 343) is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in experimental colitis in mice.
TN1238 3,4-O-Isopropylidene-shikimic acid 3,4-O-Isopropylidene shikimic acid NOS , NO Synthase
3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by tri...
TN1370 Allura Red AC Allura Red,CI 16035,FD&C RED NO. 40 Others , Estrogen/progestogen Receptor , Androgen Receptor
Allura Red AC (CI 16035) is a very important food azo dye used in the food, pharmaceutical, paper, cosmetic and textile industries.Allura Red AC promotes susceptibility to experimental colitis via mouse intestinal seroto...
T22963 McN-A 343 AChR
McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental ...
T70944 Carotegrast methyl HCl
Carotegrast methyl, also known as AJM300 and PTC-100, is an orally-active small molecule that antagonises the α4 integrin receptor. AJM300 reduces inflammation by blocking leucocyte trafficking. Oral treatment with AJM30...
T74432 Mongersen
Mongersen (GED-0301), a specific and orally active SMAD7 antisense oligonucleotide, enhances TGF-β1 activity, reducing inflammatory signals. It has been shown to alleviate experimental colitis resembling Crohn's disease ...
T63206 SR12418
SR12418 is a specific REV-ERB synthetic ligand that acts on REV-ERBα (IC50: 68 nM) and REV-ERBβ (IC50: 119 nM) and can be used to study experimental autoimmune encephalomyelitis (EAE) and colitis.
T68225 Fc 11a-2
Fc 11a-2, a benzimidazole compound, functions as an orally active, potent inhibitor of the NLRP3 inflammasome. It effectively hinders the NLRP3 inflammasome formation by blocking caspase-1 activation and consequently the...
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